Mycoplasma pneumoniae neurological symptoms

In up to 20% the CNS complications are seen without preceding pulmonary symptoms. The pathogenesis is unknown, but probably involves several mechanisms. The spectrum of clinical findings is wide, ranging from mild meningeal signs to severe neurological symptoms and a poor outcome. Mp encephalitis has a particularly high morbidity and mortality Mycoplasma pneumoniae is a common cause of upper and lower respiratory tract infections; it also affects other organ systems [ 1 ]. One of the most common extrapulmonary manifestations is a disorder of the central and/or peripheral nervous system [ 2 ] Mycoplasma pneumoniae has been associated with a wide variety of infectious and postinfectious neurologic illnesses. The agent almost certainly causes neurologic disease; however, many aspects of its association with central and peripheral nervous system injury remain controversial In some case, these infections may trigger some auto-immune diseases like some Multiple Sclerosis cases (Chlamydia pneumoniae), or other neurological disease like Inflammatory Demyelinating Polyradiculoneuropathy Severe childhood Guillain-Barré syndrome associated with Mycoplasma pneumoniae infection: a case series Mycoplasma pneumoniae has been associated with various neurologic manifestations, but exactly how the organism can cause such a wide variety of diseases is a long-standing mystery. In this respect, although pneumonia has been considered the hallmark of Mycoplasma pneumoniae infection, emerging accumulations of data have revealed that the infection can cause a number of extrapulmonary.

Patients suffering M. pneumoniae infection may have varying degrees of neurological complications at a ratio of approximately 6-7% [ 1, 2 ]. Neurological manifestations include encephalitis, transverse myelitis, acute disseminated encephalomyelitis (ADEM), Guillain-Barre syndrome, and thromboembolic stroke [ 2 ] MP symptoms are different from those of typical pneumonia caused by common bacteria, such as Streptococcus and Haemophilus. Patients usually do not have severe shortness of breath, high fever, and.. Mycoplasma pneumoniae is a type of bacteria. It often causes a mild illness in older children and young adults, but it can also cause pneumonia, an infection of the lung. The bacteria usually cause.. Socan M, Neurological symptoms in patients whose cerebrospinal fluid is culture- and/or polymerase chain reaction-positive for Mycoplasma pneumoniae. Clin Infect Dis. 2001 Jan 15;32(2):E31-5. Bencina D, et.al., Intrathecal synthesis of specific antibodies in patients with invasion of the central nervous system by Mycoplasma pneumoniae Apart from respiratory tract infections, this organism is also responsible for producing a wide spectrum of non-pulmonary manifestations including neurological, hepatic, cardiac diseases, hemolytic anemia, polyarthritis and erythema multiforme. Of the non-pulmonary manifestation, neurological manifestations are thought to be the most common

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[Neurological complications of Mycoplasma pneumoniae

  1. Mycoplasma pneumoniae is mainly recognized as a respiratory pathogen, although it is associated with the development of several extra-respiratory conditions in up to 25% of the cases. Diseases affecting the nervous system, both the peripheral (PNS) and the central nervous system (CNS), are the most severe. In some cases, particularly those that involve the CNS, M. pneumoniae-related.
  2. Mycoplasma is a bacteria (or germ) that can infect different parts of your body. Which body part is affected--your lungs, skin, or urinary tract, depends on which type of mycloplasma bacteria is.
  3. Mycoplasma pneumoniae bacteria commonly cause mild infections of the respiratory system (the parts of the body involved in breathing).The most common illness caused by these bacteria, especially in children, is tracheobronchitis (chest cold). Lung infections caused by M. pneumoniae are sometimes referred to as walking pneumonia since symptoms are generally mild
  4. Mycoplasma pneumonia in sheep usually is a mild disease. Typical clinical signs include chronic cough and dyspnea on exertion. When Pasteurella is involved, mucopurulent nasal discharge, fever, and depression also may be noted
  5. The effect of mycoplasma on the body is actually far more complex and potentially serious than previously thought. Initial symptoms include respiratory issues such as difficulty breathing, chest pain, a persistent cough, and wheezing. However, complications among already compromised patients can affect more than just the chest and lungs
  6. The most common neurological symptom was drowsiness, followed by abnormal speech/behavior, ataxia, seizure, delirium, confusion, tremor, hallucination, irritability, muscle weakness, and facial nerve paralysis
  7. The most common mycoplasma, Mycoplasma pneumoniae, has a preference for lung tissue. Initial infection with M. pneumoniae typically causes pharyngitis (sore throat), cough, fever, headache, malaise, runny nose — all the common symptoms of a basic upper respiratory infection

Mycoplasma pneumoniae is mainly responsible for causing respiratory disease but it also causes non respiratory problems such as neurological, cardiac, hepatic problems, polyarthritis, erythema multiforme and hemolytic anemia. So it's diseases are classified as pulmonary and extra pulmonary diseases Patients: We describe neurological signs and symptoms of 2 patients with M. pneumoniae-associated encephalitis in childhood. Respiratory symptoms with fever occurred in both children. They were seropositive for M. pneumoniae, but did not have the organism detected by PCR from cerebrospinal fluid. No long-term neurologic sequelae occurred J15.7 Pneumonia caused by Mycoplasma pneumoniae. And also to category J20.0 Acute bronchitis caused by mycoplasma pneumoniae. Anthroponous disease is accompanied by catarrhal and respiratory symptoms, pronounced intoxication, dyspepsia and other pathologies. This type of pneumonia manifests itself in the form of sporadic cases, and epidemic. Symptoms are usually hemiplegia and dysarthria. We report a case of a 6-year-old boy who suffered cortical blindness due to a stroke 2 days after M. pneumoniae infection. [ncbi.nlm.nih.gov] Laboratory workup revealed a Hemoglobin of 13.5 g/ dL, leukocytosis of 23,700 c/mm 3 and platelet count of 57,000 c/mm 3 The symptoms reported by patients varies: fever, malaise, headache, coughing sore throat, chills, ear pain, diarrhea, nausea / vomiting, chest pain and skin rashes with fever, cough, malaise and headache

Neurological Symptoms in Patients Whose Cerebrospinal

Common mild symptoms include sore throat, wheezing and coughing, fever, headache, rhinitis, myalgia and feelings of unease, in which symptom intensity and duration can be limited by early treatment with antibiotics Mycoplasma pneumoniae symptoms. In general, illness caused by Mycoplasma pneumoniae is mild with symptoms that appear and get worse over a period of 1 to 4 weeks. Mycoplasma pneumoniae bacteria can cause several types of infections. The most common type of illness, especially in children, is tracheobronchitis, commonly known as a chest cold Mycoplasma infections have been linked to illnesses including: multiple sclerosis 4, cancer 5, chronic fatigue syndrome and fibromyalgia 6, arthritis and hepatitus 7. Patients report a wide range of symptoms including: respiratory tract infections, fever, chest pain, neurological problems, meningitis, encephalitis, and hemolytic anemia Objective In this retrospective study, we aimed to assess frequency, types, and long-term outcome of neurological disease during acute Mycoplasma pneumoniae (M. pneumoniae) infection in pediatric patients. Materials and Methods Medical records of patients hospitalized with acute M. pneumoniae infection were reviewed

Mycoplasma pneumoniae infection: neurologic MedLink

The clinical spectrum of Mycoplasma pneumoniae CNS diseases had a wide range. Encephalitis and meningoencephalitis are the most frequent neurological manifestations, but cases of optic neuritis, transverse myelitis, Guillain-Barré syndrome (GBS), etc. have been reportedTo determine the role of M. pneumonia (using PCR and serologically test) in Cerebro Spinal Fluid (CSF) in febrile children. 2 Walter ND, Grant GB, Bandy U, et al. Community outbreak of Mycoplasma pneumoniae infection: School-based cluster of neurologic disease associated with household transmission of respiratory illnessExternal external icon. J Infect Dis. 2008;198:1365-74. 3 CDC. Mycoplasma pneumoniae respiratory illness — two rural counties, West Virginia, 2011

ness.'3 Mycoplasma pneumoniae has been described as a cause of the Guillain-Barre syndrome.'4 Oneaspect ofourpatients which differs fromthe published reports, however, is focal neurological symptoms and bizarre behavioural symptoms were also seen. It should therefore be stresse Conclusion: M. pneumoniae may reveal different neurologic complications with different radiologic findings. Iranian Journal of Pediatrics, Volume 24 (Number 5), October 2014, Pages: 647-651 Key Words: Mycoplasma Pneumonia; Transverse Myelitis; Gullaın-Barre Syndrome; Encephalitis Introduction Mycoplasma pneumoniae (M. pneumonia) is one o Mycoplasma pneumoniae is an important pathogen which causes nervous system disorders during or after the course of a respiratory tract infection. The exact pathogenic mechanism which causes neurological disorders still remains unknown. Although meningoencephalitis and acute disseminated encephalomyelitis are common complications, there are few cases of acute transverse myelitis and isolated.

Mycoplasma Pneumonia causing neurological symptoms

Mycoplasma pneumoniae (Mp) infections are well known for the classical clinical picture of primary atypical pneumonia. The infection shows a predilection for young age groups. Every fourth-fifth year Mp epidemics are seen, lasting several months particularly in autumn/wintertime. The last Mp epidemic in Denmark was seen autumn/winter 1991-1992 Neurological symptoms in patients whose cerebrospinal fluid is culture- and/or polymerase chain reaction-positive for Mycoplasma pneumoniae. Clin Infect Dis . 2001 ; 32 : E31 - 5

Neurological complications of M. pneumoniae infection are well known and include both peripheral and CNS manifestations.1 In one study with CSF culture or PCR-proved mycoplasma, the CNS symptoms were diverse and included headache, somnolence, seizures, agitation and coma. Symptoms of the mycoplasma pneumonia Mycoplasma pneumoniae is a frequent causative agent of respiratory tract infections. In 1930, M. Pneumoniae was first isolated during the study of atypical pneumonia, and in 1962 it was characterized and classified as a separate type of bacteria To the Editor: Mycoplasma pneumoniae is a common pathogen that leads to respiratory tract infections in children, often causing immune-related injuries in multiple other organs and tissues. The involvement of central nervous system has been reported in 5% to 7% of patients with M. pneumoniae infection. The clinical manifestations of M. pneumoniae encephalitis are highly heterogeneous, and more. I need help!! In April of 2015 I was diagnosed at Mayo with Mycoplasma pneumoniae with neurological complications. Since I had been through breast cancer with chemotherapy and multiple surgeries since 2013, my body was very, very weak and we were grasping for straws. I came to Mayo clinic from Indiana with a severe headache, a fever and cough DISCUSSION: Mycoplasma pneumoniae infection has been reported to cause neurological symptoms either as a primary infection or associated with pulmonary infection. Encephalitis is the most frequent neurological manifestation, but meningitis, myelitis, ataxia, and psychosis have been reported. The onset of these manifestations are usually acute, and can be fatal

Pathogenesis of Neurologic Manifestations of Mycoplasma

groups of M. pneumoniae patients were compared, selected in twos by the same anti-M. pneumoniae titer, one with and one without neurological symptoms, an-tibodies to brain were found significantly more often amongthe neurological pa-tients (Table 1) [39]. Wefractionated sera by density gradient ultracentrifugation and tested the Ig The Mycoplasma species of M. Pneumoniae and Chlamydia invading the pericardium lining of the heart, seem to be common dominators of myocarditis and pericarditis infections. Mycoplasma steroid stealing properties also make the energy producing mitochondria leaky by robbing cholesterol lipids that are necessary in mitochondrial membrane integrity Mycoplasma pneumoniae infection. Pediat Neurol 1985;1: 308-10. Introduction Mycoplasma is a well-recognized respiratory patho- gen in children and adults, which also involves other organ systems [1]. There has been an increasing number of reports of neurologic manifestations in patients with Myeoplasma infections. Up to 8.4% of hospitalize

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Mycoplasma pneumoniae infection with neurologic

  1. Introduction. Mycoplasma pneumoniae has been known to cause a wide variety of extrapulmonary diseases, including several organs of the human body, but its pathomechanisms remain largely unknown. Following is a list of extrapulmonary manifestations due to M. pneumoniae infection classified according to the three possible pathomechanisms: (1) a direct type in which the bacterium is present at.
  2. May not be associated with focal lobar consolidations that can be seen with other common pneumonia pathogens; May cause a variety of dermatological conditions in as many as 25% of patients (e.g., exanthematous rash, SJS) May also cause cardiac manifestations (e.g., carditis) or neurological symptoms (e.g., encephalitis, aseptic meningitis
  3. Allowed to progress in rare susceptible individuals (the elderly and immune-compromised individuals), mycoplasmas can cause hepatitis, pancreatitis, arthritis, heart disease, anemia, or neurologic disease. 1 Epidemics of mycoplasmal pneumonia have been reported every 4 to 8 years in the general population, but occur more often in close.
  4. Mycoplasma pneumoniae is a common cause of community-acquired pneumonia (CAP), and the disease usually has a prolonged, gradual onset. [] M pneumoniae was first isolated in cattle with pleuropneumonia in 1898.. In 1938, Reimann described the first cases of mycoplasmal pneumonia in man and coined the term primary atypical pneumonia after observing 7 patients in Philadelphia with marked.
  5. Mycoplasma pneumoniae is a cause of encephalitis in children, 1 but it remains controversial because causation is difficult to prove. The paucity of reports on isolation of M. pneumoniae from the central nervous system (CNS) favors the hypothesis of an immune-mediated inflammation in most cases. We report on a 15-year-old girl manifesting a few signs and symptoms of meningoencephalitis with.

There are several species of mycoplasma that infect the body. They have strange sounding names like: Mycoplasma fermentans, Mycoplasma hominis, or Mycoplasma pneumonia. Unfortunately, mycoplasma can infect different areas in the body and can produce symptoms of infection, mucus discharge, pain, arthritis, fatigue, or neurological problems In recent years, the resistance of Mycoplasma pneumoniae to macrolide antibiotics has increased significantly. The health systems are facing significant challenges in carrying out the diagnosis and treatment of refractory Mycoplasma pneumoniae pneumonia in children. The gastrointestinal symptoms, neurological manifestations, joint symptoms. Manifestations of Mycoplasma pneumoniae infection can range from self-limiting upper respiratory symptoms to various neurological complications, including speech and language impairment. But an association between Mycoplasma pneumoniae infection and speech and language impairment has not been sufficiently explored. In this study, we aim to investigate the association between Mycoplasma. Intravenous Immunoglobulin as a Therapeutic Option for Mycoplasma pneumoniae Encephalitis. Mebratu Daba, Peter B Kang, John Sladky, Sharatchandra S Bidari, Robert M Lawrence, 3 of whom had prodromal symptoms of infection lasting 5 to 7 days before onset of their neurologic symptoms. One patient presented with neurologic symptoms with no. Mycoplasma pneumoniae infection with neurologic complications Alberto Spalice From 71st Congress of the Italian Society of Pediatrics. Joint National Meeting SIP, SIMGePeD, Study Group on Pediatric Ultrasound, SUP Study Group on Hypertension Rome, Italy. 4-6 June 2015 Mycoplasma pneumoniae (M. pneumonia)isoneofth

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Mycoplasma Pneumonia: Causes, Symptoms, and Diagnosi

Mycoplasma pneumoniae Usually occurs in younger age groups and may be associated with neurological and systemic (e.g. rashes) symptoms. Atypical pneumonia can also have a fungal, protozoan or viral cause. In the past, most organisms were difficult to culture. However, newer techniques aid in the definitive identification of the pathogen, which. Mycoplasma pneumoniae is a common cause of community-acquired pneumonia, and many extrapulmonary manifestations have been described, but rhabdomyolysis is infrequently reported in adults. Of the few cases that have been reported in adults, it was almost exclusively seen when pneumonia was present. We report a case of a 30-year-old male who came in with complaints of fever and myalgia for three.

symptoms and to rule out other less common infectious causes. At that time, his chest X-ray showed right lower lobe pneumonia and Mycoplasma IgM to be found positive. The patient was started on a 10-day course of doxycycline. Following initiation of treatment, the patient's symptoms began to rapidly improve, his WBC along wit 2 Walter ND, Grant GB, Bandy U, et al. Community outbreak of Mycoplasma pneumoniae infection: School-based cluster of neurologic disease associated with household transmission of respiratory illnessExternal external icon. J Infect Dis. 2008;198:1365-74. 3 CDC. Mycoplasma pneumoniae respiratory illness — two rural counties, West Virginia, 2011 Mycoplasma pneumoniae is a common cause of upper respiratory tract infection, and remains the most common cause of bacterial pneumonia. A chest radiograph should be obtained in patients with. Introduction. Mycoplasma pneumoniae (M. pneumoniae) is a common respiratory tract pathogen, especially in children (1-3).Up to 40% of cases of community-acquired pneumoniae admitted to the hospital are due to M. pneumoniae infection. The central nervous system (CNS) may be one of the most susceptible sites of M. pneumoniae besides the respiratory system ()

Mycoplasma pneumoniae infection: Symptoms, treatment, and mor

Mycoplasma pneumoniae in Acute Disseminated Encephalomyelitis Bernhard Stamm,* Michael Moschopulos,* onset of infection and beginning of neurologic symptoms. A T-cell-mediated, delayed type, hypersensitivity reaction, possibly accompanied by an immune-complex type vascu pneumoniae and presented with optic neuritis without respiratory symptoms or other neurologic findings. Key words: children, optic neuritis, Mycoplasma pneumoniae. Mycoplasma pneumonia is a well-known cause of upper and lower respiratory tract infections in children including: pharyngitis, bronchitis, and pneumonia.1 M. pneumonia infection is. Neurological disease associated with Mycoplasmapneumoniaeinfection. PCR evidence against a direct invasive mechanism CGFink, MSillis, SJ Read, LButler, MPike Abstract Aims-To investigate the pathology in patients presenting with sudden onset neurological illnesses associated with Mycoplasmapneumoniaeinfection. Methods-M pneumoniae infection wa Neurological disorders associated with Mycoplasma pneumoniae infection Neurological disorders associated with Mycoplasma pneumoniae infection Sotgiu, S.; Pugliatti, M.; Rosati, G.; Deiana, G. A.; Sechi, G. P. 2003-03-01 00:00:00 Neurological syndromes caused by Mycoplasma pneumoniae (MP) infection are occasionally reported in adults, usually in the post‐infectious period, and three computed. Mycoplasma pneumoniae. Pediatr Neurol 2005; 33: 105-109. 15 Sotgiu S, Pugliatti M, Rosati G, Deiana G, Sachi G. Neurological disorders associated with Mycoplasma pneumoniae infection. Eur J Neurol 2003; 10: 165-168. 16 Gulera R, Nisar N, Chwla TC, Bismas NR. Mycoplasma pneumoniae and central nervous system complications: a review

Mycoplasma pneumonia is caused by the bacteria Mycoplasma pneumoniae ( M pneumoniae). This type of pneumonia is also called atypical pneumonia because the symptoms are different from those of pneumonia due to other common bacteria. The major features of the lungs include the bronchi, the bronchioles and the alveoli Mycoplasma infections do invade nerves, and nerve-related symptoms are among the more difficult to resolve. Dr. Nicolson states We keep seeing the suppression of information on Mycoplasma and similar intracellular bacterial infections. The world of Mycoplasma parallels the world of chronic Lyme disease in terms of the politics involved by Mycoplasma pneumoniae Paulo Pereira Christo1, Júlio Sérgio P. da Silva2, Ilana Vaula Werneck2, Sandra Lucia Dias2 Correspondence terval between the onset of respiratory symptoms and neurological manifestations ranges from 2 to 14 days, and no respiratory infection is detected in 18% of cases2 The additional supportive diagnostic feature was the presence of leuko-agglutination which is well described in mycoplasma infections. 8 As the neurological symptoms started before the initiation of treatment for pneumonia and avoidance of specific medications like quinolones and tetracyclines in this patient makes the possibility of previously.

Mycoplasma pneumoniae-induced rash and mucositis (MIRML12-Add from charts-MYCOPLASMA, LEGIONELLA, & KLEBSIELLA

Mycoplasmas - Stealth Pathogen

Hu, C. F. et al. Prognostic values of a combination of intervals between respiratory illness and onset of neurological symptoms and elevated serum IgM titers in Mycoplasma pneumoniae. Mycoplasma pneumonia as well as at least 7 other mycoplasma species have now been linked as a direct cause or significant co-factor to many chronic diseases including, rheumatoid arthritis, Alzheimer;s, multiple sclerosis, fibromyalgia, chronic fatigue, diabetes, Crohn;s Disease, ALS, nongonoccal urethritis, asthma, lupus, infertility, AIDS and. What causes mycoplasma pneumonia? Mycoplasma pneumonia is caused by the bacteria Mycoplasma pneumoniae.M. pneumoniae is considered an atypical bacteria because in most people it causes few if any, symptoms and infected people rarely seek medical attention. It is widespread worldwide and studies have shown an association of M. pneumoniae infections with climate change with a 17% rise in. Mycoplasma pneumonia (MP) is a contagious respiratory infection. Every year almost 2 million Americans are treated for MP. The disease is easily spread through contact with respiratory fluids, and it causes regular epidemics. The most common sign of infection is a dry cough

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Mycoplasma pneumonia: Clinical features and managemen

Pneumonia due to mycoplasma and chlamydophila bacteria is usually mild. Pneumonia due to legionella gets worse during the first 4 to 6 days, and then improves over 4 to 5 days. The most common symptoms of pneumonia are: Chills; Cough (with legionella pneumonia, you may cough up bloody mucus) Fever, which may be mild or hig Microbiology. Mycoplasma pneumoniae is a Mollicute, a class of bacteria that lack a cell wall. The class includes organisms that are both commensals and pathogens for animals and plants, but the human is the only known host for M. pneumoniae.Lack of a cell wall makes it possible to grow M. pneumoniae in the laboratory on cell-free media only if it is supplemented with sterols and other. I found a medical journal article stating that up to 7% of patients hospitalized with Mycoplasma pneumoniae infections have symptoms involving the Central Nervous System, and while the mechanism involved is not clear at this time, direct invasion of the nervous system, neurotoxin production and immune-mediated mechanisms have been proposed Furthermore, the feature of mycoplasma infection is the ability to become a cause of a variegated disease like diseases other than a lung, i.e., dermatitis, nephritis, arthritis and meningitis that presents neurological symptoms, or encephalitis at 25% of the infected humans Microbiology epidemiology is ever changing, but over the years Mycoplasma pneumoniae (M. pneumoniae) has remained steady as potentially the most common cause of atypical pneumonia with some sources even reporting it to be the cause of 35% of all community-acquired pneumonia (CAP) cases .M. pneumoniae infection is associated with several extrapulmonary manifestations affecting almost every.

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Five patients with evidence of focal encephalopathy are reported. In each case, evidence of mycoplasma pneumoniae infection was detected. No patient improved with conventional antibiotic therapy, but in three subjects, rapid and complete recovery did occur contemporaneously with the administration of high dose steroid therapy Mycoplasma. Mycoplasma species have been identified in ticks. Smaller than bacteria, they invade human cells and disrupt the immune system, causing fatigue, musculoskeletal symptoms, and cognitive problems. Mycoplasmas can be treated with antibiotics. Powassan virus. Powassan virus causes tick-borne encephalitis Mycoplasma pneumoniae is a common cause of community associated upper and lower respiratory tract infections most commonly in children and young adults [1].Previously thought to cause only benign respiratory disease, it can also cause severe disease and is occasionally associated with extrapulmonary complications [1-3].Among them, neurological complications of M. pneumoniae infection were. Mycoplasma pneumonia is a common cause of respiratory The spectrum of the manifestations range from haematological, dermatological, neurological, musculoskeletal, renal, cardiac and also gastrointestinal. The treatment approach has varied over time. In this report we would like to share with minimal sign and symptoms of haemolysis in a. Article: Mycoplasma Pneumoniae Encephalitis. Abstract The epidemiological, clinical, laboratory, and imaging findings of patients with M. pneumoniae encephalitis referred to the California Encephalitis Project are reported from the California Department of Health Services, Viral and Rickettsial Disease Laboratory, Richmond, CA, and the Centers for Disease Control and Prevention, Atlanta, GA

Mycoplasma Infections: Symptoms, Treatment, and Preventio

Mycoplasma Pneumoniae is an important cause of upper and lower respiratory infections in both adults and children. Extrapulmonary involvement, including dermatological, neurological, cardiac, musculoskeletal, and vasculitic involvement, has also been associated with M pneumoniae infection in humans Smith R, Eviatar L. Neurologic manifestations of Mycoplasma pneumoniae infections: diverse spectrum of diseases. A report of six cases and review of the literature. Clin Pediatr (Phila) . 2000 Apr.

BACKGROUND. Encephalitis is a complex, debilitating, and sometimes fatal neurologic condition to which children are especially prone. Mycoplasma pneumoniae , a common respiratory pathogen, has been implicated as an etiology of encephalitis. Evidence for recent or acute M pneumoniae infection has been demonstrated in limited studies of both pediatric and adult patients with encephalitis • Neuropathological findings in a patient with fatal neurological complications due to infection with Mycoplasma pneumoniae were similar to those seen in postinfectious encephalitis and acute hemorrhagic leukoencephalitis. This case supports the hypothesis that immune mechanisms play a role in the pathogenesis of neurological symptoms during. Mycoplasma pneumoniae infection in a 47-year-old man is reported. Symptoms of upper respiratory tract infection were followed by pneumonia and meningoencephalitis. In contrast to published cases with neurological manifestations of infection with M. pneumoniae, the patient was disabled by persistent cerebellar symptoms with generalized ataxia and atactic dysarthria Mycoplasma pneumoniae is a major cause of respiratory infections and a possible etiology of acute hepatitis.Acute hepatitis due to M. pneumoniae infection is often combined with presentation of pneumonia, even without lung involvement.The presentations and etiologies of M. pneumoniae-associated hepatitis with simultaneous, delayed, or without, lung involvement are different, and should be. Atypical Pneumonia is a type of lung infection that is caused by specific types of bacteria namely, Legionella pneumophila, Mycoplasma pneumoniae, and Chlamydophila pneumoniae. Individuals with this infection often have mild signs and symptoms. They are able to carry on with their daily activities without much distress Socan M. , Ravnik I. , Benč ina D. , et al: Neurological symptoms in patients whose cerebrospinal fluid is culture- and/or polymerase chain reaction-positive for Mycoplasma pneumoniae. Clin Infect Dis 2001 ;32: E31 — E35